1 Result for "

1843U89

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1843U89" in MCE Product Catalog:

Cat. No.: HY-10823
CAS No.: 139987-54-5
Synonyms: GW1843; 1843U89; OSI-7904
Domaines de recherche:  

Cancer

OSI-7904L (GW1843; 1843U89; OSI-7904) is a thymidylate synthase (TS) inhibitor with a Ki of 90 pM. OSI-7904L blocks de novo synthesis of thymidine nucleotides, DNA synthesis and induces cell death. OSI-7904L inhibits the growth of human cells, induces tumor regression, and achieves durable antitumor effects in mouse xenograft models. OSI-7904L can be used in research related to colon adenocarcinoma .
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