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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
L-dC
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "L-dC" in MCE Product Catalog:
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23 Publications Verification
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LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages .
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IMT1B (LDC203974) is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. IMT1B has anti-tumour effects .
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11 Cited Publications
LDC4297 is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 value of 0.02-1.21 μM. LDC4297 can be used for the research of infection .
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11 Cited Publications
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection .
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10 Cited Publications
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LDC1267 is a AXL/TAM/FLT3 inhibitor with IC50 values of 42 nM, 130 nM, and 63 nM against AXL, MERTK, and TYRO3, respectively. LDC1267 blocks GAS6-induced AXL phosphorylation and the downstream AKT/ERK1/2 signaling pathway. LDC1267 inhibits cancer cell proliferation, colony formation, and glioblastoma cell invasion, without causing obvious impairment of cytotoxic autophagic flux. LDC1267 exerts a synergistic effect when used in combination with Imatinib (HY-15463) in chronic myeloid leukemia models. LDC1267 can be widely applied in studies related to glioblastoma and chronic myeloid leukemia .
Cat. No.: HY-P10762
CAS No.: 2082631-84-1
Synonyms: CBP-1008; LdC 10B
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Synonyms: 2'-Deoxy-L-cytidine; L-dC
Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment .
Cat. No.: HY-18969
CAS No.: 1453833-30-1
LDC3140 is a selective CDK7 inhibitor (IC50<5 nM). By inhibiting the activity of CDK7, LDC3140 affects the regulation of the cell cycle, leading to cell cycle arrest and thus inhibiting the proliferation of tumor cells. LDC3140 can be used in the research of cancer treatment .
Cat. No.: HY-146262
CAS No.: 2411874-83-2
LDC0496 is a potent and selective EGFR inhibitor. LDC0496 possesses intense inhibitory potency toward EGFR and Her2 exon20 insertion mutations, as well as selectivity over wild type EGFR and within the kinome .
Cat. No.: HY-106205
CAS No.: 380886-96-4
Di-Val-L-dC, a prodrug of L-deoxycytidine, is a selective and specific anti-HBV agent .
Cat. No.: HY-RS07891
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LUM Human Pre-designed siRNA Set A contains three designed siRNAs for LUM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17525
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Lum Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lum gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-111674R
CAS No.: 2407782-01-6
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LDC7559 (Standard) is the analytical standard of LDC7559 (HY-111674). This product is intended for research and analytical applications. LDC7559 is a gasdermin D (GSDMD) inhibitor via blocKing neutrophil extracellular trap (NET) in the late stages .
Cat. No.: HY-184315
CAS No.: 2411873-31-7
Cat. No.: HY-P700387
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Constitutive lysine decarboxylase; EC:4.1.1.18; LdCC; ldCC; ldC; ldCH; b0186 ; JW0181
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
