LDC7559 (Standard)
LDC7559 (Standard) is the analytical standard of LDC7559 (HY-111674). This product is intended for research and analytical applications. LDC7559 is a gasdermin D (GSDMD) inhibitor via blocKing neutrophil extracellular trap (NET) in the late stages .
For research use only. We do not sell to patients.
- CAS No.: 2407782-01-6
- Formula: C20H19N3O3
- Molecular Weight:349.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2407782-01-6
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Molecular Weight 349.38
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Formula C20H19N3O3
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SMILES
COC1=C(C=CC=C1)C2=NN3C(COC(C=C(NC(C)=O)C=C4)=C4C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Spel L, et al. Gasdermin D opens the way for NETs. Nat Rev Rheumatol. 2018 Dec;14(12):690-692. [Content Brief]
[2]. Sollberger G, et al. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689. [Content Brief]
[3]. Ankit Pandeya, et al. Gasdermin D (GSDMD) as a New Target for the Treatment of Infection. Medchemcomm. 2019 Apr 4;10(5):660-667. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)