2304621-06-3
Chemical Structure
IMT1B
Synonym(s): LDC203974
- CAS No.: 2304621-06-3
- Formula:C24H21ClFNO6
- Molecular Weight:473.88
IUPAC Name: (S)-1-((R)-2-((4-(2-chloro-4-fluorophenyl)-2-oxo-2H-chromen-7-yl)oxy)propanoyl)piperidine-3-carboxylic acid
InChIKey: PFEKWBKJUBCXDT-KGLIPLIRSA-N
SMILES: O=C([C@@H]1CN(C([C@H](OC2=CC=C(C(O3)=C2)C(C4=CC=C(F)C=C4Cl)=CC3=O)C)=O)CCC1)O
Biological Activity: IMT1B (LDC203974) is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. IMT1B has anti-tumour effects[1].
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IMT1B | 99.45% | IMT1B (LDC203974) is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. IMT1B has anti-tumour effects. | ||||||||||||||||||||
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Keywords