1453834-21-3
Chemical Structure
LDC4297
- CAS 番号: 1453834-21-3
- Formula:C23H28N8O
- Molecular Weight:432.52
IUPAC Name: N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine
InChIKey: LSGRZENCFIIHNV-UHFFFAOYSA-N
SMILES: CC(C)C1=C(N2N=C1)N=C(OC3CNCCC3)N=C2NCC4=CC=CC=C4N5C=CC=N5
Biological Activity: LDC4297 is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 value of 0.02-1.21 μM. LDC4297 can be used for the research of infection[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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LDC4297 | 99.74% | LDC4297 is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 value of 0.02-1.21 μM. LDC4297 can be used for the research of infection. | ||||||||||||||||||||
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Similarity Score 0.99
HY-12653ALDC4297 hydrochloride -
Similarity Score 0.64
HY-18969LDC3140 -
Similarity Score 0.57
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Similarity Score 0.55
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Similarity Score 0.51
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HY-103712ARSamuraciclib hydrochloride (Standard) -
Similarity Score 0.50
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Similarity Score 0.49
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HY-141609IK-175 -
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