CDK7/12-IN-1
Based on 1 Customer Validation
CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 2654075-94-0
- Formula: C25H34N8O
- Molecular Weight:462.59
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 2654075-94-0
-
Appearance Solid
-
Molecular Weight 462.59
-
Formula C25H34N8O
-
Color White to light brown
-
SMILES
O[C@H]1CNCC[C@@H]1CNC2=NC3=C(C(C)C)C=NN3C(NCC4=C(C)N=C5C=C(C)C=CN54)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (216.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1617 mL | 10.8087 mL | 21.6174 mL | 54.0435 mL |
| 5 mM | 0.4323 mL | 2.1617 mL | 4.3235 mL | 10.8087 mL | |
| 10 mM | 0.2162 mL | 1.0809 mL | 2.1617 mL | 5.4044 mL | |
| 15 mM | 0.1441 mL | 0.7206 mL | 1.4412 mL | 3.6029 mL | |
| 20 mM | 0.1081 mL | 0.5404 mL | 1.0809 mL | 2.7022 mL | |
| 25 mM | 0.0865 mL | 0.4323 mL | 0.8647 mL | 2.1617 mL | |
| 30 mM | 0.0721 mL | 0.3603 mL | 0.7206 mL | 1.8015 mL | |
| 40 mM | 0.0540 mL | 0.2702 mL | 0.5404 mL | 1.3511 mL | |
| 50 mM | 0.0432 mL | 0.2162 mL | 0.4323 mL | 1.0809 mL | |
| 60 mM | 0.0360 mL | 0.1801 mL | 0.3603 mL | 0.9007 mL | |
| 80 mM | 0.0270 mL | 0.1351 mL | 0.2702 mL | 0.6755 mL | |
| 100 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5404 mL |
CDK7/12-IN-1 Related Classifications
HY-46568 Related Classifications
Powered by Bioz