CDK7/12-IN-1
Based on 1 Customer Validation
CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.66%
- CAS No.: 2654075-94-0
- 화학식: C25H34N8O
- 분자량:462.59
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 2654075-94-0
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Appearance Solid
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분자량 462.59
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화학식 C25H34N8O
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Color White to light brown
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SMILES
O[C@H]1CNCC[C@@H]1CNC2=NC3=C(C(C)C)C=NN3C(NCC4=C(C)N=C5C=C(C)C=CN54)=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 100 mg/mL (216.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1617 mL | 10.8087 mL | 21.6174 mL | 54.0435 mL |
| 5 mM | 0.4323 mL | 2.1617 mL | 4.3235 mL | 10.8087 mL | |
| 10 mM | 0.2162 mL | 1.0809 mL | 2.1617 mL | 5.4044 mL | |
| 15 mM | 0.1441 mL | 0.7206 mL | 1.4412 mL | 3.6029 mL | |
| 20 mM | 0.1081 mL | 0.5404 mL | 1.0809 mL | 2.7022 mL | |
| 25 mM | 0.0865 mL | 0.4323 mL | 0.8647 mL | 2.1617 mL | |
| 30 mM | 0.0721 mL | 0.3603 mL | 0.7206 mL | 1.8015 mL | |
| 40 mM | 0.0540 mL | 0.2702 mL | 0.5404 mL | 1.3511 mL | |
| 50 mM | 0.0432 mL | 0.2162 mL | 0.4323 mL | 1.0809 mL | |
| 60 mM | 0.0360 mL | 0.1801 mL | 0.3603 mL | 0.9007 mL | |
| 80 mM | 0.0270 mL | 0.1351 mL | 0.2702 mL | 0.6755 mL | |
| 100 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5404 mL |
CDK7/12-IN-1 Related Classifications
HY-46568 Related Classifications
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