1. Cell Cycle/DNA Damage
  2. CDK
  3. CDK7-IN-5

CDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104)).

For research use only. We do not sell to patients.

CDK7-IN-5 Chemical Structure

CDK7-IN-5 Chemical Structure

CAS No. : 1817006-50-0

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Description

CDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104))[1].

IC50 & Target[1]

CDK7

<100 nM (IC50)

In Vitro

CDK7-IN-5 (Comp 104; 72 hours) inhibits the proliferation of A673 cells with an IC50 <500 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

611.78

Formula

C34H45N9O2

CAS No.
SMILES

CC(C1=C2N(N=C1)C(NCC3=C(C=CC=C3)NCC4=CC=C(C=C4)NC(/C=C/CN(C)C)=O)=NC(OC5CCN(CC5)C)=N2)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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CDK7-IN-5 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CDK7-IN-5
Cat. No.:
HY-139986
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