Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
TAF
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "TAF" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
BAY-299, a chemical probe, is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.
2
2 Cited Publications
Target:
Research Areas:
CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.
1
Research Areas:
CeMMEC1 is an inhibitor of BRD4, and also has high affinity for TAF1, with an IC50 of 0.9 μM for TAF1, and a Kd of 1.8 μM for TAF1 (2).
Cat. No.: HY-P99196
CAS No.: 1174900-84-5
Target:
Research Areas:
Target:
Research Areas:
GNE-375 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin .
Target:
Research Areas:
UMB-32, a potent, selective BRD4 inhibitor, binds BRD4 with the Kd of 550 nM, and IC50 of 637 nM. UMB-32 also shows potency against TAF1, a bromodomain-containing transcription factor .
Cat. No.: HY-RS14162
Target:
Research Areas:
TAF15 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150239
CAS No.: 2097610-30-3
Synonyms: BAY-299N
Target:
Research Areas:
BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34 + cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively .
Cat. No.: HY-176467
CAS No.: 1926986-25-5
Research Areas:
TAF1 ligand 1 is a TAF1 ligand. TAF1 ligand 1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as ZS3-046 (HY-176457) .
Cat. No.: HY-176457
CAS No.: 3087879-97-5
Research Areas:
ZS3-046 is a TAF1 PROTAC degrader. ZS3-046 promotes the ubiquitination and degradation of TAF1. ZS3-046 activates p53 and induces apoptosis in acute myeloid leukemia (AML) cells. ZS3-046 has antitumor activity in an AML tumor xenograft mouse model .
Cat. No.: HY-RS14176
Target:
Research Areas:
TAF8 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14157
Target:
Research Areas:
TAF1 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14158
Target:
Research Areas:
TAF10 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14159
Target:
Research Areas:
TAF11 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14160
Target:
Research Areas:
TAF12 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14161
Target:
Research Areas:
TAF13 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14167
Target:
Research Areas:
TAF2 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14168
Target:
Research Areas:
TAF3 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
