2097610-30-3
2097610-30-3
Chemical Structure
BAY-364
Synonym(s): BAY-299N
- CAS No.: 2097610-30-3
- Formula:C23H19N3O4
- Molecular Weight:401.41
IUPAC Name: 6-(3-hydroxypropyl)-2-(1-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
InChIKey: OGFBLTYSHLJDTR-UHFFFAOYSA-N
SMILES: O=C1NC2=CC(N3C(C4=CC=CC5=C4C(C3=O)=CC=C5CCCO)=O)=CC=C2N1C
Biological Activity: BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34+ cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively[1].
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BAY-364 | BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34+ cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively. | |||||||||||||||||||||
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References
Keywords
