1 Result for "

120786-18-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "120786-18-7" in MCE Product Catalog:

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(±)-Huperzine A
(±)-Huperzine A
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Cat. No.: HY-17388
CAS No.: 120786-18-7
Category:  

Huperziaceae Terpenoids Sesquiterpenes Huperzia serrata (Thunb. ex Murray) Trevis. Plants

Target:  

Drug Isomer Cholinesterase (ChE) iGluR

(±)-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
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