1 Result for "

1394371-75-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1394371-75-5" in MCE Product Catalog:

Cat. No.: HY-133011
CAS No.: 1394371-75-5
Purity:  98.35%
Target:  

nAChR

Research Areas:  

Neurological Disease

nAChR agonist 1 is a potent, blood-brain-barrier-permeable, and orally active allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 μM in a Ca 2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease .
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