1 Result for "

1801151-08-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1801151-08-5" in MCE Product Catalog:

Cat. No.: HY-119886
CAS No.: 1801151-08-5
Target:  

iGluR

Research Areas:  

Neurological Disease

BMS-986169 is an inhibitor of the glutamate N-methyl-D-aspartate 2B receptor (GluN2B). BMS-986169 has a high binding affinity for the allosteric regulatory site of the GluN2B subunit, with a Ki value of 4.03-6.3 nM. BMS-986169 can inhibit the function of GluN2B receptors in Xenopus oocytes, with an IC50 value of 24.1 nM. BMS-986169 can also inhibit the activity of the hERG channel, with an IC50 value of 28.4 μM. BMS-986169 can be used in research on treatment-resistant depression .
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