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7 Results for "
2-Hydroxy atorvastatin
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "2-Hydroxy atorvastatin" in MCE Product Catalog:
Research Areas:
2-Hydroxy atorvastatin calcium salt is an orally active OATP1B1 substrate and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (3-hydroxy-3-methylglutaryl-coenzyme A reductase). 2-Hydroxy atorvastatin calcium salt enters cells via OATP1B1-mediated cellular uptake and inhibits de novo hepatic cholesterol synthesis. As an active metabolite of Atorvastatin (HY-B0589), 2-Hydroxy atorvastatin calcium salt contributes to the inhibitory activity against plasma HMG-CoA reductase. 2-Hydroxy atorvastatin calcium salt can be biotransformed into an inactive lactone form, which can be hydrolyzed back to its active acid form chemically or enzymatically. 2-Hydroxy atorvastatin (calcium salt) can be used in the research of hypercholesterolemia .
Cat. No.: HY-136346
CAS No.: 163217-74-1
Target:
Research Areas:
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
Cat. No.: HY-141987S1
Cat. No.: HY-143840S
CAS No.: 1276537-19-9
Cat. No.: HY-141987S
CAS No.: 777841-55-1
Synonyms: atorvastatin impurity K-d5
Cat. No.: HY-166549S
Cat. No.: HY-136346S
CAS No.: 265989-50-2
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