1 Result for "

210832-86-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "210832-86-3" in MCE Product Catalog:

Cat. No.: HY-D1470
CAS No.: 210832-86-3
Target:  

Fluorescent Dye

Research Areas:  

Others

BADAN is a thiol-reactive, environment-sensitive fluorescent probe used for site-specific labeling of protein cysteine residues to detect protein topology, local polarity, protein-lipid interactions, and conformational changes. The bromoacetyl group of BADAN covalently binds to cysteine thiols, and its fluorescence originates from the intramolecular charge transfer (ICT) excited state. The emission peak position varies with the polarity of the surrounding medium: it blue-shifts to approximately 488 nm in nonpolar environments (such as the hydrophobic core of lipid bilayers) and red-shifts to approximately 496-507 nm in polar environments (such as aqueous phases), independent of enzymes, pH, or membrane potential. Ex = 380-402 nm; Em = 400-600 nm .
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