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2305415-75-0

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-154042
    5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine

    		Nucleoside Antimetabolite/Analog Cancer
    5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine

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