1 Result for "

2380274-50-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2380274-50-8" in MCE Product Catalog:

15
15 Cited Publications
Cat. No.: HY-145388
CAS No.: 2380274-50-8
Purity:  99.89%
Target:  

PROTACs SWI/SNF Complex

Research Areas:  

Cancer

AU-15330 is a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 and SMARCA4. AU-15330 induces potent inhibition of tumour growth in xenograft models of prostate cancer and synergizes with the AR antagonist enzalutamide. AU-15330 induces disease remission in castration-resistant prostate cancer (CRPC) models without toxicity .
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