1 Result for "

2780353-11-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2780353-11-7" in MCE Product Catalog:

β4-TAT
β4-TAT
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Cat. No.: HY-P11231
CAS No.: 2780353-11-7
Synonyms: FUS(364-369)-TAT
Target:  

Peptides

Research Areas:  

Cancer

β4-TAT is a kind of β-sheet peptide foldamer. β4-TAT is composed of two parts: the β4 sequence (derived from the β-sheet fragment of the RRM domain of fused in sarcoma (FUS)) and the TAT sequence (a nuclear localization signal peptide that helps the entire peptide penetrate the nuclear membrane). β4-TAT influences FUS aggregation by targeting its RNA recognition motifs (RRM). β4-TAT effectively induces FUS aggregation within cells, leading to the death of cancer cells. β4-TAT can be used for the study of FUS .
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