1 Result for "

3028095-13-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3028095-13-5" in MCE Product Catalog:

Cat. No.: HY-161954
CAS No.: 3028095-13-5
Target:  

HDAC

Research Areas:  

Cancer

HDAC8-IN-12 (compound 5k) is a non-hydroxamic acid, selective inhibitor of HDAC8 (IC50: 0.12 nM) and a potent inhibitor of breast cancer. HDAC8-IN-12 triggers anti-tumor immunity by activating T cells, increasing the proportion of M1 macrophages and decreasing the proportion of M2 macrophages. HDAC8-IN-12 (50 mg/kg) exerts tumor suppressive effects in an orthotopic mouse model of breast cancer .
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