1 Result for "

3033385-59-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3033385-59-7" in MCE Product Catalog:

Cat. No.: HY-157039
CAS No.: 3033385-59-7
Purity:  97.09%
RIPK1-IN-17 is an orally active, selective RIPK1 inhibitor (Kd = 17 nM) and shows no significant inhibition to RIPK3. RIPK1-IN-17 specifically inhibits necroptosis rather than apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation. RIPK1-IN-17 protects mice from hypothermia and death. RIPK1-IN-17 can be used for the study of necroptosis-related diseases such as inflammatory response syndrome (SIRS) .
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