1 Result for "

3033401-47-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3033401-47-4" in MCE Product Catalog:

Cat. No.: HY-144624
CAS No.: 3033401-47-4
Target:  

PROTACs TAM Receptor Ras

Research Areas:  

Cancer

PROTAC Axl Degrader 1 is an orally active PROTAC degrader targeting the AXL receptor tyrosine kinase, with an IC50 of 0.92 μM against human targets. PROTAC Axl Degrader 1 induces cytoplasmic vacuolization, methuosis (macropinocytosis-induced cell death), excessive macropinosome production, and Rac1 activation. PROTAC Axl Degrader 1 inhibits the proliferation and migration of cancer cells. PROTAC Axl Degrader 1 can be used in breast cancer-related research .
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