1 Result for "

351986-85-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "351986-85-1" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-118630
CAS No.: 351986-85-1
Purity:  98.93%
Target:  

PIKfyve Autophagy

Research Areas:  

Cancer

Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca 2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation. Vacuolin-1 can induce vacuole formation and increase the percentage of enucleated cells .
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