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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
5-8F
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "5-8F" in MCE Product Catalog:
29
29 Publications Verification
Synonyms: Butanoic acid sodium; Butyric acid sodium
Category:
Target:
5
5 Cited Publications
Cat. No.: HY-18768
CAS No.: 1802088-50-1
Research Areas:
NCT-501 is a reversible, non-competitive, selective, blood-brain barrier-permeable ALDH1A1 inhibitor with an IC50 of 40 nM. NCT-501 inhibits the AKT-β-catenin signaling pathway, induces necroptosis in nasopharyngeal carcinoma cells, suppresses their proliferation and inhibits stem cell spheroid formation. NCT-501 can be used in research related to nasopharyngeal carcinoma, esophageal squamous cell carcinoma and malignant tumors .
3
Cat. No.: HY-P10412
CAS No.: 2412926-30-6
Synonyms: ANXA1-derived 11 amino acid-long peptide
Target:
Research Areas:
Cat. No.: HY-B0350AG
CAS No.: 156-54-7
Synonyms: Butanoic acid sodium (GMP); Butyric acid sodium (GMP)
Cat. No.: HY-N0836A
CAS No.: 60326-37-6
Synonyms: 11-Ketocyclopamine hydriodide
Target:
Hedgehog Wnt Akt mTOR AMPK DNA/RNA Synthesis Apoptosis Autophagy Reactive Oxygen Species (ROS) Mitochondrial Metabolism
Research Areas:
Jervine hydriodide (11-Ketocyclopamine hydriodide) is an orally active steroidal alkaloid and Hedgehog signaling pathway inhibitor. Jervine hydriodide can be isolated from Veratrum californicum. Jervine hydriodide regulates Wnt, inhibits the AKT/mTOR signaling pathway, and activates the AMPK signaling pathway. Jervine hydriodide induces DNA damage, Apoptosis, Autophagy, ROS production and Mitochondrial damage. Jervine hydriodide exhibits anti-cancer and anti-inflammatory activities. Jervine hydriodide reduces tumor growth rate and weight in xenograft models. Jervine hydriodide can be used in studies related to triple-negative breast cancer, nasopharyngeal carcinoma and non-small cell lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
