156-54-7
156-54-7
Chemical Structure
Sodium butyrate
Synonym(s): Butanoic acid sodium; Butyric acid sodium
- CAS No.: 156-54-7
- Formula:C4H7NaO2
- Molecular Weight:110.09
IUPAC Name: sodium butyrate
InChIKey: MFBOGIVSZKQAPD-UHFFFAOYSA-M
SMILES: CCCC(O[Na])=O
Biological Activity: Sodium butyrate ((Butanoic acid; Butyric acid) sodium) is an orally active HDAC inhibitor. Sodium butyrate induces hyperacetylation of core histones and affects phosphorylation of H1/H2A, thereby altering chromatin structure and regulating gene expression. Sodium butyrate can be used in research related to various cancers, inflammatory bowel disease, and sickle cell anemia[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sodium butyrate | 99.76% | Sodium butyrate ((Butanoic acid; Butyric acid) sodium) is an orally active HDAC inhibitor. Sodium butyrate induces hyperacetylation of core histones and affects phosphorylation of H1/H2A, thereby altering chromatin structure and regulating gene expression. Sodium butyrate can be used in research related to various cancers, inflammatory bowel disease, and sickle cell anemia. | ||||||||||||||||||||
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Sodium butyrate (GMP) | Sodium butyrate (GMP) refers to Sodium butyrate (HY-B0350A) of GMP grade. Small molecules of GMP grade can be used as adjuvants in cell therapy. Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity. | |||||||||||||||||||||
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Sodium butyrate (Standard) | ≥98% | Sodium butyrate (Standard) is the analytical standard of Sodium butyrate (HY-B0350A). This product is intended for research and analytical applications. Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity. | ||||||||||||||||||||
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Butyric acid-13C4 sodium | 99.6% | Butyric acid-13C4 sodium (Butyric acid-13C4 sodium) is a stable isotope labeled compound with the activity of promoting cell proliferation and regulating gene expression. Butyric acid-13C4 sodium can be used in metabolic research and compound development to help scientists gain a deeper understanding of the role of short-chain fatty acids in organisms. Butyric acid-13C4 sodium also plays an important role in nutrition and intestinal health research, especially in the regulation of probiotic function and intestinal microbiota. | ||||||||||||||||||||
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Sodium butyrate-d5 | Sodium butyrate-d5 (Butanoic acid-d5 sodium) is the deuterium labeled Sodium butyrate (HY-B0350A). Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity. | |||||||||||||||||||||
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Sodium butyrate-d3 | 99.95% | Sodium butyrate-d3 (Butanoic acid-d3 sodium) is the deuterium labeled Sodium butyrate (HY-B0350A). Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity. | ||||||||||||||||||||
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References
- [1]. Ge Y, et al. Mitigating lead-induced osteoporosis: The role of butyrate in gut-bone axis restoration. Ecotoxicology and environmental safety. 2024 Sep 15;283:116943. [Content Brief]
- [2]. Smith JG, et al. Butyric acid from the diet: actions at the level of gene expression. Crit Rev Food Sci Nutr. 1998 May;38(4):259-97.
- [3]. Januszewicz E, et al. Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. Medical oncology and tumor pharmacotherapy. 1988;5(4):259-63.
- [4]. Bretton RH, et al. Butyric acid causes morphological changes in cultured chondrocytes through alterations in the extracellular matrix. Journal of cellular physiology. 1989 Jan;138(1):197-204.
- [5]. Takenaga K, et al. Effect of butyric acid on lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells. Cancer research. 1986 Mar;46(3):1244-9.
- [6]. McGarvey TW, et al. The effect of butyric acid and retinoic acid on invasion and experimental metastasis of murine melanoma cells. Clinical & experimental metastasis. 1990;8(5):433-48.
