Butyric acid-13C4 sodium
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Butyric acid-13C4 sodium (Butyric acid-13C4 sodium) is a stable isotope labeled compound with the activity of promoting cell proliferation and regulating gene expression. Butyric acid-13C4 sodium can be used in metabolic research and compound development to help scientists gain a deeper understanding of the role of short-chain fatty acids in organisms. Butyric acid-13C4 sodium also plays an important role in nutrition and intestinal health research, especially in the regulation of probiotic function and intestinal microbiota.
For research use only. We do not sell to patients.
- Purity: 99.6%
- CAS No.: 286367-75-7
- Formula: 13C4H7NaO2
- Molecular Weight:114.06
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
All Endogenous Metabolite Isoforms
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Biological Activity
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HDAC |
Human Endogenous Metabolite |
Microbial Metabolite |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 286367-75-7
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Unlabeled Cas 156-54-7
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Appearance Solid
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Molecular Weight 114.06
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Formula 13C4H7NaO2
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Color White to off-white
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SMILES
O=[13C](O[Na])[13CH2][13CH2][13CH3]
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Synonyms
Butanoic acid-13C4 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 25 mg/mL (219.18 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Huang W, et al. Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncol Lett. 2017 Feb;13(2):921-929 [Content Brief]
[2]. Wang P, et al. Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition. Neurobiol Dis. 2017 Dec 14;111:12-25. [Content Brief]
[3]. Jaworska J, et al. The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. J Neuroinflammation. 2017 Feb 10;14(1):34 [Content Brief]
[4]. Qiu Y, et al. Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. In Vitro Cell Dev Biol Anim. 2017 Jan 27 [Content Brief]
[5]. Jung HY, et al. Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory, cell proliferation, and neuroblast differentiation. Lab Anim Res. 2016 Dec;32(4):224-230 [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.7673 mL | 43.8366 mL | 87.6732 mL | 219.1829 mL |
| 5 mM | 1.7535 mL | 8.7673 mL | 17.5346 mL | 43.8366 mL | |
| 10 mM | 0.8767 mL | 4.3837 mL | 8.7673 mL | 21.9183 mL | |
| 15 mM | 0.5845 mL | 2.9224 mL | 5.8449 mL | 14.6122 mL | |
| 20 mM | 0.4384 mL | 2.1918 mL | 4.3837 mL | 10.9591 mL | |
| 25 mM | 0.3507 mL | 1.7535 mL | 3.5069 mL | 8.7673 mL | |
| 30 mM | 0.2922 mL | 1.4612 mL | 2.9224 mL | 7.3061 mL | |
| 40 mM | 0.2192 mL | 1.0959 mL | 2.1918 mL | 5.4796 mL | |
| 50 mM | 0.1753 mL | 0.8767 mL | 1.7535 mL | 4.3837 mL | |
| 60 mM | 0.1461 mL | 0.7306 mL | 1.4612 mL | 3.6530 mL | |
| 80 mM | 0.1096 mL | 0.5480 mL | 1.0959 mL | 2.7398 mL | |
| 100 mM | 0.0877 mL | 0.4384 mL | 0.8767 mL | 2.1918 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.