2 Results for "

603151-83-3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "603151-83-3" in MCE Product Catalog:

Cat. No.: HY-103378
CAS No.: 603151-83-3
Target:  

CRFR

Research Areas:  

Neurological Disease

NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects .
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Cat. No.: HY-110056
CAS No.: 1782228-59-4
Target:  

CRFR

Research Areas:  

Neurological Disease

NBI 35965 hydrochloride is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 hydrochloride does not inhibit CRF2. NBI 35965 hydrochloride reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 hydrochloride shows anxiolytic effects .
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