2 Results for "

648903-57-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "648903-57-5" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-14985
CAS No.: 648903-57-5
Purity:  99.91%
Target:  

Syk Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

BAY 61-3606 dihydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM an IC50 of 10 nM . BAY 61-3606 dihydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell . BAY 61-3606 dihydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates . Bay 61-3606 dihydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells .
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Cat. No.: HY-76474
CAS No.: 732983-37-8
Target:  

Syk Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

BAY 61-3606 is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM . BAY 61-3606 reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell . BAY 61-3606 induces a large decrease of Syk phosphorylation in K-rn cell lysates . Bay 61-3606 sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells .
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