1 Result for "

661482-39-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "661482-39-9" in MCE Product Catalog:

Cat. No.: HY-183876
CAS No.: 661482-39-9
Target:  

Aminopeptidase

Research Areas:  

Others

LAF-153 is a Methionine Aminopeptidase-2 (MetAP-2) inhibitor with human IC50 values of 0.074 μM and 0.16 μM.LAF-153 has a t-butyl group extending into the innermost portion of the MetAP-2 cleft, a lactam ring coordinated in the enzyme’s shallow surface pocket, and three hydroxyl groups coordinating to the two cobalt ions in the enzyme’s active site .
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