1 Result for "

684645-54-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "684645-54-3" in MCE Product Catalog:

Cat. No.: HY-118931
CAS No.: 684645-54-3
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

EF-1502 is a potent and selective GABA transporter inhibitor with GAT1 and BGT1 inhibitory activity. EF-1502 produces a synergistic anti-epileptic effect when used in combination with Tiagabine (HY-B0696), a compound used to suppress epileptic seizures. The dosing combination of EF-1502 exhibited reduced anti-epileptic efficacy and dyskinesia when used with THIP (HY-10232). The mechanism of EF-1502 differs significantly from Tiagabine, suggesting a unique role in the inhibitory strategy .
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