1 Result for "

708287-29-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "708287-29-0" in MCE Product Catalog:

Referencia número: HY-158968
No. CAS: 708287-29-0
Pureza:  ≥98.0%
Target:  

MDM-2/p53

Áreas de investigación:  

Cancer

MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 (IC50=35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2, and induces K562 cell cycle arrest .
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