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A-22

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Natural
Products

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1005A22
    Poloxamer 338 (F108)

    PEG-PPG-PEG, 14600 (Average)

    		 Environmental Pollutants Biochemical Assay Reagents Others
    Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .
    Poloxamer 338 (F108)
  • HY-118773
    MreB Perturbing Compound A22 hydrochloride

    A22 hydrochloride

    		 Bacterial Infection
    MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
    MreB Perturbing Compound A22 hydrochloride
  • HY-131583
    MP265
    1 Publications Verification

    4-Chlorobenzyl carbamimidothioate hydrochloride

    		 Bacterial Infection
    MP265 (4-Chlorobenzyl carbamimidothioate hydrochloride) is a structural analogue of A22 but is less toxic. MP265 is a MreB inhibitor .
    MP265
  • HY-14347
    EBE-A22
    1 Publications Verification

    		 EGFR Cancer
    EBE-A22 is a derivative of PD153035, which can inhibit the phosphorylation of ErbB-1, but EBE-A22 does not have this activity.
    EBE-A22
  • HY-130337
    Teicoplanin A2-2

    		Antibiotic Bacterial Infection
    Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
    Teicoplanin A2-2
  • HY-118773R
    MreB Perturbing Compound A22 hydrochloride (Standard)

    A22 hydrochloride (Standard)

    		 Reference Standards Bacterial Infection
    MreB Perturbing Compound A22 hydrochloride (Standard) is the analytical standard for MreB Perturbing Compound A22 hydrochloride (HY-118773). This product is intended for research and analytical applications. MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
    MreB Perturbing Compound A22 hydrochloride (Standard)
  • HY-142672
    ATR-IN-6

    		ATM/ATR Cancer
    ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22) .
    ATR-IN-6
  • HY-N13106
    Camelliagenin A 22-angelate

    		Others Others
    Camelliagenin A 22-angelate (compound 5) is a triterpenoid isolated from the bark of birch .
    Camelliagenin A 22-angelate
  • HY-155721
    22-(4′-py)-JA

    22-4′-Pyridinecarbonyl jorunnamycin A

    		 Akt mTOR Cancer
    22-(4′-py)-JA is a semisynthetic derivative of junamycin A (JA) that can be isolated from the Thai blue sponge (Xestospongia sp.). 22-(4′-py)-JA has antimetastatic activity and can inhibit AKT/mTOR/p70S6K signaling. 22-(4′-py)-JA inhibits tumor cell invasion and tube formation in human umbilical vein endothelial cells (HUVEC), downregulates metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF). 22-(4′-py)-JA has potent anticancer activity against non-small cell lung cancer (NSCLC) .
    22-(4′-py)-JA
  • HY-RS13103
    SLC25A22 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SLC25A22 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC25A22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SLC25A22 Human Pre-designed siRNA Set A
    SLC25A22 Human Pre-designed siRNA Set A
  • HY-CE00826
    22-Methylpentacosanoyl-CoA

    22-Methylpentacosanoyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    22-Methylpentacosanoyl-CoA (22-Methylpentacosanoyl-coenzyme A) is a coenzyme A derivative.
    22-Methylpentacosanoyl-CoA
  • HY-CE00841
    22-Methyltricosanoyl-CoA

    22-Methyltricosanoyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    22-Methyltricosanoyl-CoA (22-Methyltricosanoyl-coenzyme A) is a coenzyme A derivative.
    22-Methyltricosanoyl-CoA
  • HY-CE00839
    22-Methyltetracosanoyl-CoA

    22-Methyltetracosanoyl-coenzyme A; Anteisopentacosanoyl-CoA; Anteisopentacosanoyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    22-Methyltetracosanoyl-CoA (22-Methyltetracosanoyl-coenzyme A) is a coenzyme A derivative.
    22-Methyltetracosanoyl-CoA
  • HY-CE01266
    CoA(22:2(13Z,16Z))

    Coenzyme A(22:2(13Z,16Z))

    		 Biochemical Assay Reagents Metabolic Disease
    CoA(22:2(13Z,16Z)) (Coenzyme A(22:2(13Z,16Z))) is a coenzyme A derivative .
    CoA(22:2(13Z,16Z))

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