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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
ACTH release
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "ACTH release" in MCE Product Catalog:
7
7 Publications Verification
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Antalarmin (hydrochloride) is an oral active non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome .
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Cat. No.: HY-P0060
CAS No.: 16960-16-0
Synonyms: Tetracosactrin; ACTH(1–24)
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Cat. No.: HY-P0060A
CAS No.: 60189-34-6
Synonyms: Tetracosactrin acetate; ACTH(1–24) acetate
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Synonyms: SPR001; LY2371712
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Tildacerfont (SPR001; LY2371712) is an orally active, blood-brain barrier-penetrant selective corticotropin-releasing factor type 1 (CRF1) receptor antagonist. Tildacerfont selectively blocks CRF1 receptors, thereby inhibiting the release of pituitary adrenocorticotropic hormone (ACTH). Tildacerfont can be used in research related to congenital adrenal hyperplasia .
Cat. No.: HY-P1558A
Synonyms: Adrenocorticotropic Hormone (11-24) acetate
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Cat. No.: HY-P1245
CAS No.: 192387-39-6
Synonyms: Neuropeptide NPFF (human)
Cat. No.: HY-113603S
CAS No.: 2762751-36-8
Synonyms: SPR001-d8; LY2371712-d8
Cat. No.: HY-P4786
CAS No.: 1815618-01-9
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Cat. No.: HY-P3687
CAS No.: 83930-34-1
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Cat. No.: HY-P3683
CAS No.: 158535-55-8
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Cat. No.: HY-103378
CAS No.: 603151-83-3
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NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects .
Cat. No.: HY-12132
CAS No.: 202579-74-6
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DMP 904 is a noncompetitive full corticotropin-releasing factor receptor (CRFR) antagonist. DMP 904 can inhibit CRF-stimulated adenylate cyclase activity and ACTH release. DMP 904 exhibits anti-depressant and anti-anxiety activity .
Cat. No.: HY-P3685
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Cat. No.: HY-P3489
CAS No.: 12427-33-7
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Cat. No.: HY-P1245A
CAS No.: 2924824-03-1
Synonyms: Neuropeptide NPFF (human) acetate
Cat. No.: HY-P4012
CAS No.: 40944-53-4
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Cat. No.: HY-P3684
CAS No.: 195628-97-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
