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Cat. No.: HY-P2281A

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Atrial natriuretic factor (1-28) (human, porcine) TFA

Name: Atrial natriuretic factor (1-28) (human, porcine) TFA
Brand: MedChemExpress
SKU: HY-P2281A
Price: 425.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Atrial natriuretic peptide (1-28) TFA)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC₅₀ of 1.2 nM.

For research use only. We do not sell to patients.

Purity : 98.23%
Formula: C₁₂₇H₂₀₅N₄₅O₃₉S₃.xC₂HF₃O₂
Molecular Weight:3080.46 (free base)

Storage:

Sealed storage, away from moisture.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Atrial natriuretic factor (1-28) (human, porcine) TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Endogenous Metabolite Isoforms :

Chemical Information

Appearance Solid
Molecular Weight 3080.46 (free base)
Formula C₁₂₇H₂₀₅N₄₅O₃₉S₃.xC₂HF₃O₂
Color White to off-white
Synonyms

Atrial natriuretic peptide (1-28) TFA
Sequence

Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr
Sequence Shortening

SLRRSSCFGGRMDRIGAQSGLGCNSFRY
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Journal Impact Factor

Sci Adv

Transcriptional determinants of lipid mobilization in human adipocytes. [Abstract]

2024 Jan 5;10(1):eadi2689. PMID: 38170777

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. B M Fontoura, et al. Atrial natriuretic factor receptors in cultured renomedullary interstitial cells. Am J Physiol. 1990 Apr;258(4 Pt 1):C692-9. [Content Brief]

[2]. T T Tan, et al. ANF(1-28) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of beta EP-LI release from AtT-20 cells. J Endocrinol. 1994 Nov;143(2):R1-4. [Content Brief]

[3]. D M Pollock, et al. Beneficial effect of the ANF analog A68828 on recovery from ischemic acute renal failure. Ren Fail. 1992;14(2):141-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Atrial natriuretic factor (1-28) (human, porcine) TFA

1 Cited Publications

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Atrial natriuretic factor (1-28) (human, porcine) TFA

Publications Citing Use of MedChemExpress (MCE) Atrial natriuretic factor (1-28) (human, porcine) TFA

All Endogenous Metabolite Isoforms