1 Result for "

AMG 837 calcium

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AMG 837 calcium" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-13967B
CAS No.: 1259389-38-2
Purity:  99.00%
Research Areas:  

Metabolic Disease

AMG 837 calcium hydrate is an orally active, selective GPR40/FFA1 agonist with an EC50 of 1.5 nM against human GPR40. AMG 837 calcium hydrate stimulates insulin secretion in a glucose-dependent manner, and effectively improves glycemic control in both normal and diabetic rodent models . AMG 837 calcium hydrate binds to the BacA protein and impairs the survival and replication of Brucella. AMG 837 calcium hydrate can be used in research related to type 2 diabetes and brucellosis .
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