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2 Results for "
Antibacterial agent 39
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Antibacterial agent 39" in MCE Product Catalog:
Cat. No.: HY-139756
CAS No.: 1426572-46-4
Antibacterial agent 39, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime .
Cat. No.: HY-178912
Research Areas:
Anti-MRSA agent 39 is an orally active ClpX modulator that binds Staphylococcus aureus caseinolytic protease X (SaClpX) with high affinity (Kd = 3.6 μM). Anti-MRSA agent 39 exerts antibacterial effects through temperature-dependent inhibition of cell division. Anti-MRSA agent 39 elicits profound metabolic dysregulation in methicillin-resistant Staphylococcus aureus (MRSA), manifesting as significantly reduced ATP levels, elevated reactive oxygen species (ROS), and decreased NAD+/NADH ratio, and accelerates bacterial lysis rates in MRSA ATCC 33591. Anti-MRSA agent 39 significantly increases the proportion of MRSA cells in the mitotic phase, and the cells exhibit obvious morphological abnormalities. Anti-MRSA agent 39 can be used for the study of invasive MRSA infections .
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