2 Results for "

BChE-IN-25

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BChE-IN-25" in MCE Product Catalog:

Cat. No.: HY-157520
CAS No.: 79183-25-8
Target:  

Cholinesterase (ChE)

Research Areas:  

Others

BChE-IN-25 (compound 4I) is a selective BChE inhibitor (IC50: 3.77μM), which is 22 times more selective for BChE than AChE .
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Cat. No.: HY-168731
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

AChE/BChE-IN-25 (Compound 6e) is the orally active inhibitor for hAChE and eqBChE with IC50 of 7.9 nM and 0.79 nM. AChE/BChE-IN-25 exhibits antioxidant activity, that scavenges free radical with IC50 of 22.91 μM. AChE/BChE-IN-25 exhibits neuroprotective effects by reducing mitochondrial and cellular oxidative stress in the Drosophila Alzheimer's disease model. AChE/BChE-IN-25 ameliorates Scopolamine (HY-N0296)-induced spatial and cognitive memory impairment in mouse model .
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