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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
BMX-IN-4
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "BMX-IN-4" in MCE Product Catalog:
Cat. No.: HY-187351
CAS No.: 3132799-96-0
Target:
Research Areas:
BMX-IN-4 is a covalent BMX kinase inhibitor with an IC50 of 1.78 nM and a Ki of 0.158 μM. BMX-IN-4 forms a covalent bond with BMX kinase. BMX-IN-4 is applicable to the research of hepatocellular carcinoma .
TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC50 of 13 nM. TAS0728 also shows IC50s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for BMX、HER4、BLK、EGFR、JAK3、SLK and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2, HER3, and downstream effectors .
Cat. No.: HY-111553R
CAS No.: 2088323-16-2
Target:
Research Areas:
TAS0728 (Standard) is the analytical standard of TAS0728 (HY-111553). This product is intended for research and analytical applications. TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC50 of 13 nM. TAS0728 also shows IC50s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for BMX、HER4、BLK、EGFR、JAK3、SLK and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2, HER3, and downstream effectors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
