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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
BPTF
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "BPTF" in MCE Product Catalog:
1
1 Cited Publications
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BPTF-IN-BZ1, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM).
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GSK1379725A is a selective BPTF ligand with a Kd of 2.8 uM, showing no binding activity for Brd4 .
Cat. No.: HY-141703A
Purity: ≥97.0%
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DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation .
Cat. No.: HY-126299
CAS No.: 2662454-54-6
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NVS-BPTF-1, a chemical probe, is a selective inhibitor for bromodomain and PHD finger containing transcription factor (BPTF), with KD of 71 nM .
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TP-238 hydrochloride is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases .
Cat. No.: HY-141703
CAS No.: 2758411-61-7
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DC-BPi-11 is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 shows remarkable inhibition against leukemia cell proliferation .
Cat. No.: HY-145431
CAS No.: 2359618-49-6
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(S)-GSK1379725A (compound AU1) is a selective bromodomain and PHD finger containing transcription factor (BPTF) bromodomain inhibitor with a Kd of 2.8 μM. (S)-GSK1379725A shows to be selective for BPTF over BRD4 bromodomain. (S)-GSK1379725A shows antimalarial activity .
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DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM .
Cat. No.: HY-114205
CAS No.: 2415263-04-4
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TP-238 is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases .
Cat. No.: HY-115663
CAS No.: 902156-98-3
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C620-0696 is an inhibitor targeting the brom domain of BPTF, with a KD value of 35.5 μM. C620-0696 can exert cytotoxic effects on A549 and H358 cells, inhibiting the expression of c-Myc. C620-0696 inhibits cell migration and colony formation, and induces apoptosis and cell cycle arrest. C620-0696 can be used in the research of non-small cell lung cancer .
Cat. No.: HY-RS01586
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BPTF Human Pre-designed siRNA Set A contains three designed siRNAs for BPTF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16684
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Bptf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bptf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23119
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Bptf Rat Pre-designed siRNA Set A contains three designed siRNAs for Bptf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-111575
CAS No.: 723245-31-6
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DCB29 is a selective inhibitor of the BPTF bromodomain, with an IC50 value of 13.2 μM. DCB29 can be used for the study of the BPTF-related diseases (such as bladder cancer, colorectal cancer, melanoma, leukemia, and other cancers) .
Cat. No.: HY-P701611
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BPTF; Nucleosome-Remodeling Factor Subunit BPTF; Prev. FALZ; Bromodomain And PHD Domain Transcription Factor; FAC1; Nucleosome Remodeling Factor, Large Subunit; Fetal Alzheimer Antigen; Fetal Alz-50 Reactive Clone 1; NURF301; BPTF Protein; Bromodomain And
Cat. No.: HY-P701612
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BPTF; Nucleosome-Remodeling Factor Subunit BPTF; Prev. FALZ; Bromodomain And PHD Domain Transcription Factor; FAC1; Nucleosome Remodeling Factor, Large Subunit; Fetal Alzheimer Antigen; Fetal Alz-50 Reactive Clone 1; NURF301; BPTF Protein; Bromodomain And
Cat. No.: HY-178697
CAS No.: 2758411-53-7
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DC-BPi-07 is a selective BPTF inhibitor with an IC50 value of 16.0 nM against BPTF-H4. DC-BPi-07 can be used in the research of leukemia .
Cat. No.: HY-160286
CAS No.: 2001082-11-5
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BI-7190 is a selective BPTF inhibitor (Kd = 3.5 nM). BI-7190 can be used in the research of cancer .
Cat. No.: HY-155891
CAS No.: 874594-37-3
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BET-IN-18 (Compound 3) is a pan-BET bromodomain small-molecule inhibitor, with Ki values of 0.69 μM and 0.37 μM, and Kd values of 1.6 μM and 8.4 μM against BrdT (1) and Brd4 (1) bromodomains, respectively. BET-IN-18 potently and competitively inhibits the binding of the known BET inhibitor (+)-JQ1 (HY-13030) to Brd4 (1) and BrdT (1), with IC50 values of 1.0 μM and 2.3 μM, respectively. BET-IN-18 also competitively inhibits the binding of acetylated histone substrates to Brd4 (1) (IC50 = 0.90 μM). BET-IN-18 can be used in the research of multiple myeloma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
