902156-98-3
Chemical Structure
C620-0696
- CAS No.: 902156-98-3
- Formula:C24H24N4O3
- Molecular Weight:416.47
IUPAC Name: 5-((3-(dimethylamino)propyl)amino)-3-((furan-2-ylmethyl)amino)-6H-anthra[1,9-cd]isoxazol-6-one
InChIKey: WWVDPOHZQPMVPV-UHFFFAOYSA-N
SMILES: O=C1C2=C(C3=C4C1=C(NCCCN(C)C)C=C(NCC5=CC=CO5)C4=NO3)C=CC=C2
Biological Activity: C620-0696 is an inhibitor targeting the brom domain of BPTF, with a KD value of 35.5 μM. C620-0696 can exert cytotoxic effects on A549 and H358 cells, inhibiting the expression of c-Myc. C620-0696 inhibits cell migration and colony formation, and induces apoptosis and cell cycle arrest. C620-0696 can be used in the research of non-small cell lung cancer[1].
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C620-0696 | C620-0696 is an inhibitor targeting the brom domain of BPTF, with a KD value of 35.5 μM. C620-0696 can exert cytotoxic effects on A549 and H358 cells, inhibiting the expression of c-Myc. C620-0696 inhibits cell migration and colony formation, and induces apoptosis and cell cycle arrest. C620-0696 can be used in the research of non-small cell lung cancer. | |||||||||||||||||||||
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