26 Results for "

C21 steroid

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "C21 steroid" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-113405
CAS No.: 641-77-0
Purity:  99.62%
21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD) .
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Cat. No.: HY-N2103
CAS No.: 191729-43-8
Tenacissoside G is a C21 steroid from the stems of Marsdenia tenacissima. Tenacissoside G reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells .
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Cat. No.: HY-N1375
CAS No.: 84745-94-8
Qingyanshengenin (NSC 379666; compound 2), a pregnane glycoside, is a C21 steroidal aglycone isolated from the root of Cynanchumot ophyllum (Asclepiadaceae). Qingyanshengenin has anti-cancer activity .
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Cat. No.: HY-N2102
CAS No.: 191729-44-9
Tenacissoside I is a C21 steroid from the Marsdenia tenacissima, which is detected at relatively high level in M. tenacissima .
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Cat. No.: HY-113215
CAS No.: 302-91-0
Purity:  99.53%
Synonyms: 5a-Tetrahydrocortisol
Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes .
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Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
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Cat. No.: HY-Z8245
CAS No.: 145-15-3
Synonyms: Progesterone EP impurity C
20b-Dihydroprogesterone (Compond III) is a C-21 steroid found in water beetles Cybister limbatus, C. tripunctatus and C. confuses .
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Cat. No.: HY-N0582
CAS No.: 106758-54-7
Otophylloside B, a C-21 steroidal glycoside isolated from Qingyangshen. Otophylloside B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Otophylloside B has antiepileptic activity .
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Cat. No.: HY-132271
CAS No.: 23214-93-9
Chloramphenicol 1-acetate (Compound Ⅲ) is a microbial transformation product of Chloramphenicol (HY-B0239) by Streptomyces coelicolor. Chloramphenicol 1-acetate is the major product of Chloramphenicol acetyltransferase I (CATI) by regioselective acetylation of C21 hydroxy groups in steroids .
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Cat. No.: HY-113405R
CAS No.: 641-77-0
21-Deoxycortisol (Standard) is the analytical standard of 21-Deoxycortisol (HY-113405). This product is intended for research and analytical applications. 21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD) .
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Cat. No.: HY-N0581
CAS No.: 106644-33-1
Qingyangshengenin A, a C-21 steroidal glycoside isolated from the roots of Cynanchum otophyllum Schneid, has antiepileptic activity .
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Cat. No.: HY-113405S1
CAS No.: 2479914-04-8
Purity:  98.59%
21-Deoxycortisol-d8 is the d8-labeled 21-Deoxycortisol (HY-113405). 21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD) .
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Cat. No.: HY-113405S
21-Desoxycortisol-d4 is the d4-labeled 21-Deoxycortisol (HY-113405). 21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD) .
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Cat. No.: HY-N12720
CAS No.: 1800029-53-1
Cynanoside J is a C21 steroidal glycosides that can be obtained from Cynanchum taihangense. The IC50 values of Cynanoside J for HL-60, THP1, and Caco2 are 6.38, 5.82, and 6.76 μM, respectively. Cynanoside J can be used in cancer research .
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Cat. No.: HY-N18006
CAS No.: 250217-53-9
Otophylloside C is a C21 steroidal glycoside compound found in the root of Gynostemma pentaphyllum .
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Cat. No.: HY-N17609
CAS No.: 1393815-04-7
Sarsaligates A is a C21-steroid ester with anticancer activity. Sarsaligates A can be used in research related to promyelocytic leukemia, gastric cancer, breast cancer, and pancreatic cancer .
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Cat. No.: HY-N19936
CAS No.: 1802801-83-7
Qinyangshengenin-3-O-β-D-digitoxopyranoside is a C21 steroidal glycoside that can be found in the whole herb of Prunella vulgaris Linn. Qinyangshengenin-3-O-β-D-digitoxopyranoside can be used for research of leukemia and lung cancer .
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Cat. No.: HY-184046
CAS No.: 1084954-73-3
Caudatin-3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside is a naturally derived C21 steroidal glycoside that induces cytotoxicity in leukemia cells with a IC50 of 15.7 µM. Caudatin-3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside can be used in leukemia research .
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Cat. No.: HY-N21838
CAS No.: 641-85-0
Category:  

Microorganisms Steroids

Target:  

Drug Derivative

Allopregnane is a C21-type 5α-stane steroid derivative, a potent inhibitor of estrogen-induced chicken oviduct growth, and is present in the starfish Asterias amurensis .
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