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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
C26
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "C26" in MCE Product Catalog:
3
3 Cited Publications
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T-26c, a chemical probe, is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes .
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ELOVL1-IN-2 is an elongation of very long chain fatty acid 1 (ELOVL1) enzyme inhibitor, ELOVL1-IN-2 shows weak ELOVL1 inhibition (IC50=21 μM) and moderate potency in a primary cellular assay (HEK293 C26 IC50=6.7 μM) .
Cat. No.: HY-160004
CAS No.: 1523493-53-9
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PXL770 is an orally active, direct allosteric AMP-activated protein kinase (AMPK) activator. PXL770 decreases C26:0 levels, improves mitochondrial respiration, reduces expression of proinflammatory genes and induces expression of compensatory transporters (ABCD2/3) in ALD fibroblasts/lymphocytes. PXL770 normalizes plasma VLCFA levels, significantly reduces elevated VLCFA levels in brain and spinal cord in Abcd1 KO mice. PXL770 improves glycemia, dyslipidemia, and insulin resistance in ob/ob and high-fat diet (HFD)-fed mice. PXL770 can be used for the study of X-linked adrenoleukodystrophy (ALD), autosomal dominant polycystic kidney disease and nonalcoholic steatohepatitis (NASH) .
Cat. No.: HY-165075S
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MTDH-SND1 blocker 1 (compound C26-A6) is an inhibitor of the MTDH-SND1 protein. MTDH-SND1 blocker 1 inhibits cancer metastasis .
Cat. No.: HY-W590674
CAS No.: 121459-09-4
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C26 Ceramide is a lipid featuring two hydrophobic tails, one saturated and the other unsaturated. Ceramides may be used in developing lipid nanoparticles or liposomes.
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C26 D,L-Carnitine-d9 is deuterium labeled C26 D,L-Carnitine.
Cat. No.: HY-165075
CAS No.: 221097-57-0
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C26 Sphingomyelin (d18:1/26:0) is a biochemical reagent.
Cat. No.: HY-134127S2
CAS No.: 2743078-84-2
Synonyms: C26:0 methyl ester-d3; Ceic acid methyl ester-d3; Ceotic acid methyl ester-d3; SFE 27:0-d3
Cat. No.: HY-139085A
Purity: ≥95.0%
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XL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog .
Cat. No.: HY-139085B
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XL388-C2-amide-PEG9-NH2 TFA is an intermediate used in the synthesis of C26-linked Rapamycin analog .
Cat. No.: HY-W777920
CAS No.: 182362-38-5
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C26-Dihydro ceramide is a dihydroceramide containing a C26 very-long-chain fatty acid. C26-Dihydro ceramide can be used for research on various neurological disorders including Alzheimer's disease, Parkinson's disease, multiple sclerosis, depression, and anxiety disorders .
Cat. No.: HY-N4162
CAS No.: 1260173-73-6
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Triterpenes Terpenoids Meliaceae Extract Plants Disease Research Fields Aphanamixis polystachya (Wall.) R. N. Parker Cancer
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Cat. No.: HY-173598
CAS No.: 930993-54-7
T3SS-1-IN-1 (Compound C26) is a T3SS-1 inhibitor. T3SS-1-IN-1 inhibits the secretion of SipA and the activity of HilD (IC50 values are 29.2 and 16.9 μM, respectively). T3SS-1-IN-1 can be used for the study of anti-virulence of Salmonella .
Cat. No.: HY-151459
CAS No.: 2831498-09-8
VEGFR-2/DHFR-IN-2 (compound 5b) is an inhibitor of VEGFR-2 and DHFR with IC50s of 0.623 and 9.085 μM, respectively. VEGFR-2/DHFR-IN-2 exhibits good cytotoxic activities against C26, HepG2, and MCF7 cancer cell lines with IC50 values of 3.59-8.38 μM. VEGFR-2/DHFR-IN-2 can be used for the research of cancer .
Cat. No.: HY-162873
MEK/RAF-IN-1 (Compound 16b) is an inhibitor of both MEK and RAF. It shows potent inhibition with IC50 values of 28 nM for MEK1, and 3 nM each for BRAF and BRAFV600E. MEK/RAF-IN-1 demonstrates significant antitumor activity, effectively inhibiting cell proliferation in vitro against MIA PaCa-2 (G12C KRAS), HCT116 (G13D KRAS), and C26 (G12D KRAS) cells. Additionally, it inhibits tumor growth in xenograft mouse models of colorectal cancer .
Cat. No.: HY-151458
CAS No.: 2831498-15-6
VEGFR-2/DHFR-IN-1 (compound 8b) is an inhibitor of VEGFR-2 and DHFR with IC50s of 0.384 and 7.881 μM, respectively. VEGFR-2/DHFR-IN-1 shows good antibacterial activities against Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA and MRSA with MIC values of 16, 16, 16, 8, and 16 μg/mL, respectively. VEGFR-2/DHFR-IN-1 exhibits good cytotoxic activities against C26, HepG2, and MCF7 cancer cell lines with IC50 values of 2.97-7.12 μM. VEGFR-2/DHFR-IN-1 can be used for the research of cancer .
Cat. No.: HY-CE00012
Synonyms: C26:4(Omega-6)-CoA
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(11Z,14Z,17Z,20Z)-Hexacosatetraenoyl-CoA (C26:4(Omega-6)-CoA) is an unsaturated fatty acyl-CoA.
Cat. No.: HY-CE00015
Synonyms: C26:5(omega-3)-CoA
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(11Z,14Z,17Z,20Z,23Z)-Hexacosapentaenoyl-CoA (C26:5(omega-3)-CoA) is an unsaturated fatty acyl-CoA.
Cat. No.: HY-CE00014
Synonyms: 3-Oxo-C26:5(omega-3)-CoA
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(11Z,14Z,17Z,20Z,23Z)-3-Oxohexacosapentaenoyl-CoA (3-Oxo-C26:5(omega-3)-CoA) is an unsaturated fatty acyl-CoA.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
