869296-13-9
869296-13-9
Chemical Structure
T-26c
- CAS No.: 869296-13-9
- Formula:C24H21N3O6S
- Molecular Weight:479.51
IUPAC Name: 4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid
InChIKey: CDQRIIUMNLMHRH-UHFFFAOYSA-N
SMILES: COC1=CC=CC(CNC(C2=NC(SC=C3COCC4=CC=C(C(O)=O)C=C4)=C3C(N2)=O)=O)=C1
Biological Activity: T-26c, a chemical probe, is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].
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T-26c | 99.52% | T-26c, a chemical probe, is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes. | ||||||||||||||||||||
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T-26c (Standard) | ≥98% | T-26c (Standard) is the analytical standard of T-26c (HY-100518). This product is intended for research and analytical applications. T-26c, a chemical probe, is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.74
HY-100518AT 26c sodium -
Similarity Score 0.67
HY-115721Antimalarial agent 2 -
Similarity Score 0.54
HY-122624MMP13-IN-2 -
Similarity Score 0.48
HY-154868MMP-13-IN-1 -
Similarity Score 0.46
HY-167079AOPC-18750 hydrochloride -
Similarity Score 0.45
HY-120514JNc-440 -
Similarity Score 0.45
HY-167079OPC-18750 -
Similarity Score 0.45
HY-149946HDAC-IN-57 -
Similarity Score 0.45
HY-142690AHDAC-IN-27 dihydrochloride -
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