1. Metabolic Enzyme/Protease
  2. MMP

T-26c 

Cat. No.: HY-100518
Handling Instructions

T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes.

For research use only. We do not sell to patients.

T-26c Chemical Structure

T-26c Chemical Structure

CAS No. : 869296-13-9

Size Price Stock
5 mg USD 120 Get quote
10 mg USD 190 Get quote
25 mg USD 380 Get quote
50 mg USD 650 Get quote

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Customer Review

View All MMP Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • References

Description

T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].

IC50 & Target

IC50: 6.75 pM (MMP-13)[1]

In Vitro

T-26c significantly inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1β and oncostatin M stimulated cartilage[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0855 mL 10.4273 mL 20.8546 mL
5 mM 0.4171 mL 2.0855 mL 4.1709 mL
10 mM 0.2085 mL 1.0427 mL 2.0855 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

479.51

Formula

C₂₄H₂₁N₃O₆S

CAS No.

869296-13-9

SMILES

COC1=CC=CC(CNC(C2=NC(SC=C3COCC4=CC=C(C(O)=O)C=C4)=C3C(N2)=O)=O)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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T-26c
Cat. No.:
HY-100518
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T-26c

Cat. No.: HY-100518