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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
C5 convertase
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "C5 convertase" in MCE Product Catalog:
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1 Cited Publications
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Research Areas:
Compound C5-IN-1 (Compound 7) is a selective allosteric inhibitor of complement component protein C5. Compound C5-IN-1 prevents C5 from being cleaved by C5 convertase, inhibits the cleavage of C5 into C5a and C5b, and thus blocks the formation of membrane attack complex (MAC). Compound C5-IN-1 has an IC50 of 0.77 μM and 5 nM in 50% human whole blood and 2% human serum to block MAC deposition induced by zymosan, respectively. Compound C5-IN-1 can be used to study diseases related to complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
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Cat. No.: HY-P99965
CAS No.: 1917321-26-6
Synonyms: SKY59; RO7112689; RG-6107
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Cat. No.: HY-NP004
Synonyms: CVF
Cat. No.: HY-153098
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Research Areas:
ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
Cat. No.: HY-153098A
Purity: 94.13%
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Research Areas:
ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
Cat. No.: HY-153785
Purity: 92.50%
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NH2-C6-ARC186 sodium is a modified ARC186 (HY-153098) with NH2-C6 that can be coupled to other peptides or molecules. ARC186 is a aptamer and a highly potent complement inhibitor that function by blocking the convertase-catalyzed activation of C5 .
Cat. No.: HY-P991022
CAS No.: 2842046-67-5
Synonyms: NM8074
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097
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Cat. No.: HY-P705281
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2
Cat. No.: HY-P705282
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2
Cat. No.: HY-P700697
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2; ARMD14; CO2
Species:
Source:
Cat. No.: HY-P705191
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2; ARMD14; CO2
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Source:
Cat. No.: HY-P705290
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2; ARMD14; CO2
Cat. No.: HY-P705296
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C2; C3/C5 convertase; C2; ARMD14; CO2
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
