Copy Link Print Information

Ruxoprubart

(Synonyms: NM8074)
Customer Review

Based on 1 Customer Validation

Ruxoprubart (NM8074) is an inhibitor of complement factor B (Bb subunit). Ruxoprubart selectively binds to active Bb to inhibit the alternative complement pathway without affecting the classical complement pathway. By blocking the activities of AP C3 and C5 convertases, Ruxoprubart effectively inhibits red blood cell hemolysis and reduces C3b deposition, thereby preventing intravascular and extravascular hemolysis. Ruxoprubart can be used in research related to paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, C3 glomerulopathy, and IgA nephropathy.

For research use only. We do not sell to patients.

  • Purity: 95.541%
  • CAS No.: 2842046-67-5
  • Molecular Weight:145.982 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ruxoprubart
  • Experimental Validation Results for Ruxoprubart
  • Ruxoprubart Chemical Structure
    Ruxoprubart Chemical Structure
CAS No.: 2842046-67-5
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Ruxoprubart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
100 mg

Get Quote In-stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized Complement Factor B/CFB Protein, Human (HEK293, His, HY-P7813) can bind Ruxoprubart. The EC50 for this effect is 24.9 ng/mL.

  • Ruxoprubart Chemical Structure
    1/16
  • Ruxoprubart
  • Immobilized Complement Factor B/CFB Protein, Human (HEK293, His, HY-P7813) can bind Ruxoprubart. The EC50 for this effect is 24.9 ng/mL.
  • IgG1-kappa