1. Immunology/Inflammation
  2. Complement System
  3. Complement C5-IN-1

Complement C5-IN-1 

Cat. No.: HY-128342
Handling Instructions

Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 µM.

For research use only. We do not sell to patients.

Complement C5-IN-1 Chemical Structure

Complement C5-IN-1 Chemical Structure

CAS No. : 2365402-67-9

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Description

Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 µM[1].

Molecular Weight

444.52

Formula

C₂₄H₃₂N₂O₆

CAS No.

2365402-67-9

SMILES

COC1=C(OCCCC(C)C)C=C(NC(N[[email protected]](C2=C(OC)C=CC=C2)C)=O)C(C(O)=O)=C1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Complement C5-IN-1
Cat. No.:
HY-128342
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