36 Results for "

C6 Ceramide

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "C6 Ceramide" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-19542
CAS No.: 124753-97-5
Synonyms: C6-Cer; N-Hexanoylsphingosine
Target:  

Apoptosis

Research Areas:  

Cancer

C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
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1
1 Cited Publications
Cat. No.: HY-P1103
CAS No.: 1030384-98-5
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-W356116
CAS No.: 94885-02-6
Synonyms: Nbd-Ceramide
C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-W356117
CAS No.: 94885-03-7
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity .
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Cat. No.: HY-D1574
CAS No.: 94885-04-8
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
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Cat. No.: HY-19542S1
Synonyms: C6-Cer-d11; N-Hexanoylsphingosine-d11
C6 Ceramide-d11 is deuterated labeled C6 Ceramide (HY-19542). C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
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Cat. No.: HY-139062
CAS No.: 486991-52-0
Synonyms: C6 Ceramide (d18:1/6:0) Urea; Cer(d18:1/6:0) Urea; D-erythro-Urea-C6-Ceramide
Research Areas:  

Cancer

C6 Urea Ceramide (Cer(d18:1/6:0) Urea) is an inhibitor of neutral ceramidase. C6 Urea Ceramide increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and HT-29 colon cancer cells. C6 Urea Ceramide (5-10 μM) inhibits proliferation of HT-29 cells and induces apoptosis and autophagy, but is not toxic to non-cancerous cells. C6 Urea Ceramide decreases total and phosphorylated β-catenin levels in HT-29 and HCT116 cells, and induces colocalization of β-catenin with the 20S proteasome. C6 Urea Ceramide (1.25, 2.5, and 5 mg/kg) reduced tumor growth and increased C16, C18, C20, and C24 ceramide levels in tumor tissues in the HT-29 mouse xenograft model.
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Cat. No.: HY-D1749
CAS No.: 114301-96-1
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.
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Cat. No.: HY-116609
CAS No.: 189894-80-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides . C6 L-threo Ceramide significantly inhibits IL-4 production in T cells. Anti-allergic agents .
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Cat. No.: HY-147178
CAS No.: 114301-95-0
Target:  

Fluorescent Dye

Research Areas:  

Others

C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain .
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Cat. No.: HY-D1573
CAS No.: 114301-99-4
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .
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Cat. No.: HY-116585
CAS No.: 189894-79-9
Research Areas:  

Neurological Disease

C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate (HY-18739) in EL4 T cells .
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Cat. No.: HY-N15946
CAS No.: 2389048-46-6
Category:  

Lipids

Photoclick C6 ceramide is a clickable sphingolipid.
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Cat. No.: HY-D1576
Target:  

Fluorescent Dye

Research Areas:  

Others

C6 NBD L-threo-dihydroceramide is a dihydro-ceramide isomer labeled with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD), can be used to detect ceramide.
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Cat. No.: HY-19542S
CAS No.: 2692624-22-7
Ceramide C6-d7 is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells .
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Cat. No.: HY-173541
Synonyms: C6 Dihydro Ceramide (m18:0/6:0)
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

C6 Dihydro 1-deoxyceramide (m18:0/6:0) (C6 Dihydro ceramide (m18:0/6:0)) is an analog of ceramide .
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Cat. No.: HY-176102
Synonyms: N-Hexanoyl-D-erythro-sphingosine alkyne
Research Areas:  

Others

C6 Ceramide (d18:1/6:0) alkyne is an ω-alkyne derivative of C6 ceramide. The terminal alkyne group can be used in click chemistry reactions to tag C6 ceramide with fluorescent or biotinylated labels, allowing the analysis of the metabolism and biological activity of C6 ceramide.
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Cat. No.: HY-172666F
Synonyms: Biotin Ceramide (d18:0/6:0)
C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
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Cat. No.: HY-N16325
CAS No.: 3091879-76-1
Category:  

Lipids

Target:  

Fluorescent Dye

Golgi-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Golgi-Laurdanmimics the structure NBD C6 Ceramide that can be used for the study of the Golgi apparatus .
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