189894-79-9
189894-79-9
Chemical Structure
C6 D-Threo Ceramide (d18:1/6:0)
- CAS No.: 189894-79-9
- Formula:C24H47NO3
- Molecular Weight:397.63
IUPAC Name: N-((2R,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexanamide
InChIKey: NPRJSFWNFTXXQC-KHZUJUORSA-N
SMILES: OC[C@@H](NC(CCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O
Biological Activity: C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate (HY-18739) in EL4 T cells[1][2].
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C6 D-Threo Ceramide (d18:1/6:0) | C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate (HY-18739) in EL4 T cells. | |||||||||||||||||||||
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References
- [1]. Park J, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13(7):2589-95. [Content Brief]
- [2]. Irie F, et al. Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations. J Neurosci Res. 1998 Nov 15;54(4):475-85. [Content Brief]
