94885-02-6
Chemical Structure
C6 NBD Ceramide
Synonym(s): Nbd-ceramide
- CAS No.: 94885-02-6
- Formula:C30H49N5O6
- Molecular Weight:575.74
IUPAC Name: 5-(piperidin-1-yl)pyridin-2-amine
InChIKey: HZIRBXILQRLFIK-VPZZKNKNSA-N
SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)CO
Biological Activity: C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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C6 NBD Ceramide | 99.33% | C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism. | ||||||||||||||||||||
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- [1]. Lipsky NG, et al. A vital stain for the Golgi apparatus. Science. 1985 May 10;228(4700):745-7. [Content Brief]
- [2]. Brandán YR, et al. Influence of sphingomyelin metabolism during epithelial-mesenchymal transition associated with aging in the renal papilla. J Cell Physiol. 2022 Jul 31. [Content Brief]
- [3]. Pagano RE. A fluorescent derivative of ceramide: physical properties and use in studying the Golgi apparatus of animal cells. Methods Cell Biol. 1989;29:75-85. [Content Brief]
Keywords
