16 Results for "

CCL1

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "CCL1" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-122219
CAS No.: 688352-84-3
Purity:  98.04%
Target:  

CCR

Research Areas:  

Inflammation/Immunology

R243 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects [1] .
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2
2 Cited Publications
Cat. No.: HY-124416
CAS No.: 850330-18-6
Purity:  99.80%
Target:  

CCR

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca 2+ concentrations [1] .
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2
2 Cited Publications
Cat. No.: HY-P73913
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine 1; CCL1; SCYA1; TCA-3
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P7198
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuI-309/CCL1; C-C motif chemokine 1; SCYA1
Species:  
Source:  
CHO
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Cat. No.: HY-P990914
CAS No.: 2865822-82-6
Synonyms: GS-1811; JTX-1811

Target:  

CCR

Research Areas:  

Inflammation/Immunology Cancer

Denikitug (GS-1811; JTX-1811) is a humanized monoclonal antibody against CCR8 receptor with a KD of 16.8 pM. Denikitug specifically binds to human CCR8, inhibits CCL1-induced downstream CCR8 signaling. Denikitug selectively depletes cells expressing CCR8 via antibody-dependent cellular cytotoxicity (ADCC). Denikitug promotes anti-tumor immunity and can be used for the research of cancer and immunology [1].
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Cat. No.: HY-144197
CAS No.: 723304-76-5
Purity:  99.50%
Target:  

CCR

Research Areas:  

Neurological Disease

CCR8 antagonist 1 (Compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM. CCR8 antagonist 1 has high safety and metabolic stability. CCR8 antagonist 1 can be used to study diseases such as asthma and multiple sclerosis [1].
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Cat. No.: HY-174772
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL1 mRNA encodes the human C-C motif chemokine ligand 1 (CCL1) protein, a member of the CC subfamily. CCL1 is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils.
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Cat. No.: HY-RS02080
Research Areas:  

Others

CCL1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16818
Research Areas:  

Others

Ccl1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23259
Research Areas:  

Others

Ccl1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccl1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P73914
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine 1; CCL1; SCYA1; TCA-3
Species:  
Source:  
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Cat. No.: HY-P704667
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; CCL1; SCYA1
Species:  
Source:  
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Cat. No.: HY-P70463
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; CCL1; SCYA1
Species:  
Source:  
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Cat. No.: HY-P704666
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; CCL1; SCYA1
Species:  
Source:  
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Cat. No.: HY-P705140
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; CCL1; SCYA1
Species:  
Source:  
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Cat. No.: HY-P991944

Target:  

CCR

Research Areas:  

Cancer

ZL-1218 is a selective humanized IgG1 antibody, targeting CCR8. ZL-1218 induces antibody-dependent cellular cytotoxicity (ADCC), leading to NK cell-mediated depletion of CCR8-expressing regulatory T cells (Tregs). ZL-1218 blocks the binding of the CCR8 ligand CCL1 to CCR8 and reduces Treg recruitment by inhibiting the chemotaxis of CCR8 + cells. ZL-1218 reduces intratumoral Treg levels in a dose-dependent manner. ZL-1218 exerts enhanced antitumor activity when combined with the anti-PD-1 antibody. ZL-1218 can be used for solid tumour research [1] .
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