1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR
  3. ML604086

ML604086 

Cat. No.: HY-124416
Handling Instructions

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.

For research use only. We do not sell to patients.

ML604086 Chemical Structure

ML604086 Chemical Structure

CAS No. : 850330-18-6

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Description

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

IC50 & Target

CCR8[1][2].

Molecular Weight

508.63

Formula

C₂₇H₃₂N₄O₄S

CAS No.

850330-18-6

SMILES

O=C(NC1=C2C=CC=CC2=C(S(=O)(N[[email protected]]3[[email protected]](C)CN(C([[email protected]@H](N)C)=O)CC3)=O)C=C1)C4=CC=CC=C4C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ML604086
Cat. No.:
HY-124416
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