1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR
  3. ML604086

ML604086 

Cat. No.: HY-124416 Purity: 99.89%
Handling Instructions

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.

For research use only. We do not sell to patients.

ML604086 Chemical Structure

ML604086 Chemical Structure

CAS No. : 850330-18-6

Size Price Stock Quantity
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

IC50 & Target

CCR8[1][2].

Molecular Weight

508.63

Formula

C₂₇H₃₂N₄O₄S

CAS No.

850330-18-6

SMILES

O=C(NC1=C2C=CC=CC2=C(S(=O)(N[[email protected]]3[[email protected]](C)CN(C([[email protected]@H](N)C)=O)CC3)=O)C=C1)C4=CC=CC=C4C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 125 mg/mL (245.76 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9661 mL 9.8303 mL 19.6607 mL
5 mM 0.3932 mL 1.9661 mL 3.9321 mL
10 mM 0.1966 mL 0.9830 mL 1.9661 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

ML604086ML 604086ML-604086CCRCC chemokine receptorInhibitorinhibitorinhibit

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ML604086
Cat. No.:
HY-124416
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